High-fat diet wistar rats

Statistical differences between groups were evaluated by independent sample Student's t test using SPPS version 9. This pathogenesis is multifactorial and includes lipid metabolism alterations, with an aberrant accumulation of triglycerides, mitochondrial dysfunction, inflammation, and oxidative stress OS [ 18 ].

Long term highly saturated fat diet does not induce NASH in Wistar rats

More fat is stored and the individual moves along the scale toward obesity. Hwang D Modulation of the expression of cyclooxygenase-2 by fatty acids mediated through toll-like receptor 4-derived signaling pathways. Consequently, the metabolic profile in type 2 diabetes patients will depend on the duration of their disease an early vs late stage of type 2 diabetes.

To determine whether proanthocyanidins can protect against dyslipidemia induced by a high-fat diet HFD and to address the mechanisms that underlie this hypolipidemic effect. TG content was measured as previously described for plasma samples.

Interestingly, with all studied doses, all ratios paragraphs tend very nearly towards the same form with an increasing exposure of gamma irradiation. It has been recently confirmed [ 7 ] that the consumption of high amounts of refined carbohydrates in food and beverage increases the risk of dyslipidaemia [ 8 ], obesity [ 46 ], insulin resistance [ 9 ], and heart disease [ 10 ].

Mediators of Inflammation

Oligomycin 1. Hyang S. Hence, the model can effectively be applied to determine how consumption of an HF diet modifies the negative feedback system that controls body fat. Article Information.

Metabolic and oxidative stress markers in Wistar rats after 2 months on a high-fat diet

Insulin resistance and excessive accumulation of lipids is strongly associated with non-alcoholic fatty liver disease NAFLDwhich represents the hepatic manifestation of a systemic impairment of the insulin network [ 14 ].

Plasma and liver lipids were measured by colorimetric and gravimetric analysis. In conclusion, the results of the present investigation demonstrates that CA has an anti-obesity effect, which is evidenced by decreased lipid levels in serum and by the improvement of histological alterations in the adipose tissue and heart of obese rats.

Compared with rats fed the nonpurified diet, the HF rats had even more marked differences in these variables. These cells play an important role in several mechanisms such as cytokines secretion, metabolism and hemostasis [ 28 ].

J Clin Invest More specifically, we describe a model that controls key variables to better reach unambiguous conclusions regarding the role of dietary fat in the etiology of obesity. Using iron lids to hit the cage until the wistar rats spook or squeeze, twice; Wet Feeding: Vibrating the cage in order to make the wistar rats can not stand steadily, twice; Pinpricking:(HOMA-IR) in relation to the insulin tolerance test (ITT) in a model of insulin-resistance in Wistar rats induced by a week high-fat diet.

Materials and methods: A total of 30 male Wistar rats weighing g were allocated into a high-fat diet group (HFD) (55% fat-enriched chow, ad lib, n = 15) and a.

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12/1/ · Male Wistar rats were randomly divided into four groups, namely, the normal control (NC) which received standard rodent diet, the high fat diet (HFD) which received high fat diet only, the high fat diet treated with T.

crispa (HFDTC), and the high fat diet treated with orlistat (HFDO). After sixteen weeks of treatment, blood and organs were Cited by: 4. Journal of Ethnopharmacology 69 () 21–25 Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats S.

The model of rat lipid metabolism disorder induced by chronic stress accompanying high-fat-diet

Ghasi a,*, E. Nwobodo b, J.O. Ofili c a Department of Pharmacology and Therapeutics, College of Medicine, Uni6ersity of Nigeria, Enugu, Nigeria b Department of Physiology, College of Health Sciences, Nnamdi Azikiwe Uni6ersity, Nnewi.

The primary objective of this research project is explore a possible adipogenic effect of iron and/or copper in albino Wistar rats kept on standard (STD) and high-fat (HFD) diets. The female Wistar rats in the study were divided into eight experimental groups (n = 6).Cited by: 7/15/ · However, a direct comparison between Wistar and Sprague-Dawley (SD) Rat as models of high-fat (HF) diet-induced obesity has not been adequately evaluated so far.

Wistar and SD rats were assigned for 2 experimental groups for 17 weeks: standard (St) and high-fat (HF) diet groups. THE EFFECT OF CINNAMALDEHYDE ON HIGH FAT DIET INDUCED WISTAR RATS – A PRELIMINARY STUDY D Haripriya and K Vijayalakshmi * Department of Biochemistry, Bharathi Women’s (Autonomous) College, Chennai -Tamil Nadu, India.

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physiological changes, lipid profiles and histopathological changes that occurred in.

High-fat diet wistar rats
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